Acute massive pulmonary embolism is a life-threatening emergency that is associated with a high mortality rate. Patients presenting with cardiac arrest could be saved by emergency pulmonary embolectomy. Pulmonary embolism is common and has a high mortality if not treated. Many patients who die from pulmonary embolism have not been diagnosed premortem, a shortcoming related to the variability in clinical presentation, inaccurate risk assessment, and lack of access to advanced imaging technology.
The risk of pulmonary embolism is significantly higher in patients treated with low-potency first-generation antipsychotics, clozapine and olanzapine. The suggested mechanisms include enhanced platelet aggregation, prolactin-mediated production of antiphospholipid antibodies, venous stasis due to decreased ambulation, and procoagulant consequences of weight gain and obesity.for more information